Recent study between gum disease and Rheumatoid arthritis
Periodontal disease and rheumatoid arthritis: the evidence accumulates for complex pathobiologic interactions
Purpose of review
This review was conducted to focus on the recent clinical and translational research related to the associations between periodontal disease and rheumatoid arthritis.
There is a growing interest in the associations between oral health and autoimmune and inflammatory diseases. A number of epidemiologic studies have described associations between rheumatoid arthritis and periodontal disease. Recent clinical studies continue to support these reports, and are increasingly linked with biological assessments to better understand the nature of these relationships. A number of recent studies have evaluated the periopathogenic roles of Porphyromonas gingivalis, the oral microbiome, and mechanisms of site-specific and substrate-specific citrullination. These are helping to further elucidate the interactions between these two inflammatory disease processes.